{
  "citation": "Specimen Registry v0.0.7 (2026). Maintained by Michael Gonzalez with AI assistance. https://specimenregistry.org. Data licensed under CC BY 4.0.",
  "license": "https://specimenregistry.org/license",
  "version": "0.0.12-neon",
  "publication": {
    "id": "10.1038/srep23559",
    "title": "Identification of a new hominin bone from Denisova Cave, Siberia using collagen fingerprinting and mitochondrial DNA analysis",
    "authors": [
      "Brown, S.",
      "Higham, T.",
      "Slon, V.",
      "Pääbo, S.",
      "Meyer, M.",
      "Douka, K.",
      "Brock, F.",
      "Comeskey, D.",
      "Procopio, N.",
      "Shunkov, M.",
      "Derevianko, A.",
      "Buckley, M."
    ],
    "year": 2016,
    "journal": "Scientific Reports",
    "volume": null,
    "issue": null,
    "pages": "6, article 23559",
    "publication_date": "2016-03-29T00:00:00.000Z",
    "open_access_url": "https://www.nature.com/articles/srep23559",
    "pmc_id": null,
    "pubmed_id": null,
    "abstract": "DNA sequencing has revolutionised our understanding of archaic humans during the Middle and Upper Palaeolithic. Unfortunately, while many Palaeolithic sites contain large numbers of bones, the majority of these lack the diagnostic features necessary for traditional morphological identification. As a result the recovery of Pleistocene-age human remains is extremely rare. To circumvent this problem we have applied a method of collagen fingerprinting to more than 2000 fragmented bones from the site of Denisova Cave, Russia, in order to facilitate the discovery of human remains. As a result of our analysis a single hominin bone (Denisova 11) was identified, supported through in-depth peptide sequencing analysis and found to carry mitochondrial DNA of the Neandertal type. Subsequent radiocarbon dating revealed the bone to be >50,000 years old. Here we demonstrate the huge potential collagen fingerprinting has for identifying hominin remains in highly fragmentary archaeological assemblages, improving the resources available for wider studies into human evolution.",
    "crossref_verified_at": null,
    "verification_state": "draft",
    "verification_notes": "Migrated from ingest file: T1.9_Brown_2016.md",
    "fts_tsv": "'000':145B '11':115B '2000':85B '50':144B 'age':64B 'analysi':17A,109B,125B 'appli':76B 'archaeolog':164B 'archaic':25B 'assemblag':165B 'avail':169B 'bone':6A,42B,87B,113B,141B 'brock':188C 'brown':176C 'buckley':198C 'carri':129B 'cave':9A,93B 'circumv':71B 'collagen':12A,80B,154B 'comeskey':190C 'contain':38B 'd':191C 'date':138B 'demonstr':150B 'denisova':8A,92B,114B 'depth':122B 'derevianko':196C 'diagnost':49B 'discoveri':100B 'dna':16A,18B,131B 'douka':186C 'evolut':175B 'extrem':68B 'f':189C 'facilit':98B 'featur':50B 'fingerprint':13A,81B,155B 'found':127B 'fragment':86B 'fragmentari':163B 'high':162B 'higham':178C 'hominin':5A,112B,159B 'huge':152B 'human':26B,65B,102B,174B 'identif':1A,55B 'identifi':117B,158B 'improv':166B 'in-depth':120B 'k':187C 'lack':47B 'larg':39B 'm':185C,195C,199C 'major':44B 'mani':35B 'method':78B 'meyer':184C 'middl':29B 'mitochondri':15A,130B 'morpholog':54B 'n':193C 'neandert':134B 'necessari':51B 'new':4A 'number':40B 'old':147B 'order':96B 'palaeolith':32B,36B 'peptid':123B 'pleistocen':63B 'pleistocene-ag':62B 'potenti':153B 'problem':73B 'procopio':192C 'pääbo':182C 'radiocarbon':137B 'rare':69B 'recoveri':60B 'remain':66B,103B,160B 'resourc':168B 'result':58B,106B 'reveal':139B 'revolutionis':21B 'russia':94B 'sequenc':19B,124B 'shunkov':194C 'siberia':10A 'singl':111B 'site':37B,90B 'slon':180C 'studi':172B 'subsequ':136B 'support':118B 'tradit':53B 'type':135B 'understand':23B 'unfortun':33B 'upper':31B 'use':11A 'v':181C 'wider':171B 'year':146B",
    "created_at": "2026-07-26T18:01:51.160Z",
    "updated_at": "2026-07-27T02:16:42.538Z",
    "study_type": null
  },
  "specimens": [
    {
      "id": "denisova-11",
      "common_name": "Denisova 11",
      "taxonomic_assignment": "Neanderthal-Denisovan F1 hybrid",
      "assignment_method": "aDNA-nuclear",
      "verification_state": "pending-verification"
    }
  ],
  "analyses": [
    {
      "id": "3f80131a-e392-4756-a69c-3f3405c35e89",
      "specimen_id": "denisova-11",
      "method": "paleoproteomics",
      "dating_method": null,
      "lab": "University of Oxford (Higham/Douka group) / University of Manchester (Buckley group)",
      "result_summary": "ZooMS applied at scale (2000+ bones) — screened non-diagnostic bone fragments and identified a single hominin bone (Denisova 11). Established ZooMS as the standard method for hominin-bone discovery in highly fragmentary Palaeolithic assemblages.",
      "verification_state": "draft"
    },
    {
      "id": "f0182da2-a98d-4adf-827e-1eb9e9efba05",
      "specimen_id": "denisova-11",
      "method": null,
      "dating_method": null,
      "lab": null,
      "result_summary": "Denisova 11 mtDNA identified as Neanderthal-type. This assignment was based only on the maternal lineage; genomic reanalysis in Slon 2018 revealed paternal Denisovan ancestry.",
      "verification_state": "draft"
    }
  ]
}